structural studies on the interaction of nano-sio2 with lysozyme

Authors

b. shareghi

s. farhadian

m. salavati-niasari

abstract

the interaction between nano-sio2 and lysozyme was investigated by the method of uv-visible  detection and fluorescence spectroscopic techniques. the thermal denaturation of lysozyme has been investigated in the presence and absence of nano-sio2 over the temperature range (293-373) k in different buffers and ph values, using temperature scanning spectroscopy. the presence of nano-sio2 caused the destabilization of lysozyme resulting in a decrease in the temperature of unfolding with an increase in nano-sio2 concentration.

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Journal title:
journal of nanostructures

Publisher: university of kashan

ISSN 2251-7871

volume 1

issue 3 2012

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